Diethyltoluamide

NOMENCLATURE
Common name: Diethyltoluamide
IUPAC name: N,N-diethyl-m-toluamide
Other names: DEET; N,N-Diethyl-3-Methylbenzamide; Diethyl Toluamide; Diethyl-M-Toluamide; 3-Methyl-N,N-Diethylbenzamide
CAS RN: [134-62-3]

PHYSICAL CHEMISTRY
Purity: 99% min. Appearance: achromatic or amber color liquid. S.g./density: 0.992~0.999/25, V.p: <0.01 mm Hg @25, B.p: 291.7 at 760 mm Hg, F.p: 155. Solubility: Soluble in most organic Solvents. Insoluble in water.

APPLICATIONS
Uses: Used as an insect repellent, as a resin solvent and in film formers. It is also used to impregnate clothing and as a leech repellent.

MAMMALIAN TOXICOLOGY
Draize test, rabbit, eye: 10 mg Moderate; Draize test, rabbit, skin: 500 mg Moderate; Inhalation, rat: LC₅₀ = 5950 mg/m³; Oral, mouse: LD₅₀ = 1470 mg/kg; Oral, rabbit: LD₅₀ = 1584 mg/kg; Oral, rat: LD₅₀ = 1950 mg/kg; Skin, rabbit: LD₅₀ = 3180 uL/kg; Skin, rat: LD₅₀ = 5 gm/kg

ECOTOXICOLOGY
Fish toxicity: LC₅₀ (96 hr) cichlid 120-150 ppm. After 96 hours, glutathione levels in liver, kidney and gills were raised. Invertebrate toxicity: EC₅₀ (5 min) Photobacterium phosphoreum 67.9 ppm Microtox test.

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