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Common name flutriafol (BSI, ANSI, draft E-ISO, (m) draft F-ISO)
IUPAC name (RS)-2,4'-difluoro-a-(1H-1,2,4-triazol-1-ylmethyl)benzhydryl alcohol
Chemical Abstracts name (?-a-(2-fluorophenyl)-a-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol
CAS RN [76674-21-0]
PHYSICAL CHEMISTRY
Mol. wt. 301.3 M.f. C16H13F2N3O Form White, crystalline solid. M.p. 130 ºC V.p. 7.1 ´ 10-6 mPa (20 ºC) KOW logP = 2.3 (20 ºC) Henry 1.65 ´ 10-8 Pa m3 mol-1 (calc.) S.g./density 1.41 g/ml (25 ºC) Solubility In water 130 mg/l (pH 7, 20 ºC). In acetone 190, dichloromethane 150, methanol 69, xylene 12, hexane 0.3 (all in g/l, 20 ºC).
APPLICATIONS
Biochemistry Inhibits ergosterol biosynthesis (steroid demethylation inhibitor), causing fungal cell wall collapse and inhibition of hyphal growth.
Mode of action Contact and systemic fungicide with eradicant and protective action. Absorbed by the foliage, with translocation acropetally in the xylem.
Uses Control of a broad spectrum of leaf and ear diseases (including Erysiphe graminis, Rhynchosporium secalis, and Septoria, Puccinia, and Helminthosporium spp.) in cereals, at 125 g a.i./ha. Also used in non-mercurial seed treatment formulations to control the major soil-borne and seed-borne diseases of cereals.