Thiocyclam

Chemical Abstracts name: N, N - dimethyl-1 ,2,3-3 Thioxanthenone cyclohexane-5-amine

CAS RN: [31895-22-4]

PHYSICAL CHEMISTRY

Mol. wt.: 271.4; base 181.3; Form: Colourless, odourless solid. M.p.: 125-128 ºC (decomp). V.p.: 0.545 mPa (20 ºC). KOW: logP = -0.07 (unstated pH). Henry: 1.8x10-6 Pa m3 mol-1  (calc.) S.g./density: 0.6; Solubility: In water 84 (pH <3.3, 23 ºC), 44.1 (pH 3.6, 20 ºC), 16.3 (pH 6.8, 20 ºC) (all in g/l). In dimethyl sulfoxide 92, methanol 17, ethanol 1.9, acetonitrile 1.2, acetone 0.5, ethyl acetate, chloroform <1, toluene, hexane <0.01 (all in g/l, 23 ºC). Stability: Stable during storage, shelf life (20 ºC) 2 y; degraded by sunlight, DT50 2-3 d in surface waters; hydrolysis DT50 (25 ºC) 0.5 y (pH 5), 5-7 d (pH 7-9). pKa: pK a1 3.95, pK a2 7.00

APPLICATIONS

Insecticidal ring for selective pesticides, a stomach poison, smoothly, the suction effect to the top conduction, Coleoptera and Lepidoptera control pests for the duration of seven to 14 days, can also control parasitic nematodes, such as white rice sharp nematodes, for some crops and white rust disease also Sui a certain efficacy. To control three Borer, leafroller, Chilo suppressalis, rice thrips, leafhoppers, gall midge, planthopper, Myzus persicae, apple aphids, red spider apple, pear-Caterpillar, Phyllocnistis citrella, vegetable pests. Especially potato leaf beetle control, the amount of the active ingredient to the acrylate.

MAMMALIAN TOXICOLOGY

Toxicity LD50 (mg / kg): the original drug acute oral toxicity LD50 (mg / kg): 303 male rats, female rats 274 male mice 145.8, 158 female mice. Carp 40th (48h) 1.42mg / L, maximum allowable residues of rice WMA, ADI for 0.008mg/kg. Insecticidal Central right-rat acute oral toxicity LD50 310mg/kg male mice acute oral toxicity LD50 273mg/kg male rats acute skin toxicity LD50 1000. 90 days without feeding the role of the pilot: 100mg/kg feed for rats, dogs ip feed. Carp 40th (96h) 1.03mg / L and Cyclops in 40mg / L and above. Allow residues: rice 0.1 mg / L, fruit 0.3 mg / L, tea 10 mg / L, respectively. ADI is 0.05mg/kg. Security intervals for 15 days.

ENVIRONMENTAL FATE

Right Silkworm toxicity, long duration, and some smoked kill, sericulture in the region should pay attention to pesticide methods used cautiously. A moderately toxic to bees. Traits: colorless, tasteless crystal.